【摘要】 研究了胍类与α-氰基-α,β-不饱和腈的反应,制得九个新化合物,经UV、IR、MS、~1HNMR光谱及元素分析,确定了结构。经钙通道阻滞试验,表明二氢嘧啶类似物具有一定的生物活性。更多还原

【Abstract】 The reaction of Guanidines with α-cyano-α,β-unsaturated nitriles was studied, and nine newcompounds were synthesized. The structures of these compounds were identified by UV, IR, MSand~1H NMR spectra as well as elemental analysis. Calcium channel antagonist test showed dihydropyri-midines exhibited certain biological activity.更多还原