【摘要】 将膀胱上皮移植到105只同种异体豚鼠的腹直肌表面,观察诱导成骨过程中的组织学及组织化学的变化。观察到膀胱上皮移植后,向四周延伸围成囊泡,在囊泡壁周围受体结缔组织内形成异位骨组织。最早的成骨区域常位于移行区上皮深面,与移植上皮固有膜形成的透明区相毗邻或者接近,以后向透明区和增生上皮深面扩展,本文对异位骨成骨细胞的来源和移行上皮可能释放的诱导因子等问题进行了讨论。更多还原

【Abstract】 Pieces of the vesical epithelium were transplanted on the rectus of 105 healthy guineapigs and the histological and histochemical changes have been observed during the induced ossification. After transplantatioil the vesical epithelium enveloped a cyst by preliferation and spreading. The heterotopic bone formed in the host’s granulation near the wall of the cyst. The earliest osteogenic area was usually in the deep side of the epithelium ofthe transitional region and then spread to the hyalized ared which was formed in the lamina properia of the vesical mucosa. The origin of the osteoblasts and a possible inducing agent released by transitional epitheliumare discussed.更多还原