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硬膜外腔小剂量氯胺酮用于术后镇痛的临床观察
CLINICAL OBSERVATION ON POSTOPERATIVE ANELGESIC BY LOW DOSE EPIDURAL INFUSION OF KETAMINE
【摘要】 我们选择30例硬膜外麻醉患者,术后于硬膜外腔一次注入小剂量氧胺酮0.5mg/kg,对其术后镇痛效果和生理影响进行临床观察,并作对照。观察结果表明:(1)实验组术后镇痛时间明显延长(最长5h55min),(2)神志清醒,仅少数有轻度嗜睡现象,(3)对呼吸和循环系统无显著影响,(4)无尿潴留发生。有3例术后有恶心呕吐。因此,作者认为,硬膜外腔小剂量氯胺酮可产生脊髓镇痛作用,且没有产生麻醉剂量的全身影响,是一种较好的术后镇痛方法。
【Abstract】 This study investigates analgesic and Physiological effects of ketaminc on thirty epidural anesthesia patients infused a single dose of ketamine 0.5mg/kg into their epidural space. The principal findings were the following. (1) The time of anelgesic was prolonged notably in the experiment group. ( 2 ) Most patients were perfectly conscious but a few with light somnolence. ( 3 ) There was no association with the respiratory system and circulatory system.(4 ) Retention of urine didn’t occur and nousea and vomiting were present Only in three Patients after the infusion on the basis of these observations. We conclude; that spinal cord analgesic can be Produced by a low dose epidural infusion of ketamine, and it is a better technique for relieving postoperative Pain.
- 【文献出处】 蚌埠医学院学报 ,Journal of Bengbu Medical College , 编辑部邮箱 ,1987年04期
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