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吡喹酮治疗人体华支睾吸虫病的疗效观察

THE EFFICACY OF TREATING HUMAN CLONORCHIASIS WITH PRAZIQUENTEL

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【作者】 陈兴保胡守峰郑诗莲燕尽平孙敦柱

【Author】 Chen Shingbao et al (Department of Parasitology, Bengbu Medical College, Anhui)

【机构】 蚌埠医学院寄生虫学教研室安徽省怀远县教育局卫生保健所安徽省怀远县教育局卫生保健所

【摘要】 本文用吡喹酮总剂量210mg/kg的3日疗法治疗了203例华支睾吸虫病忠者,治疗后30、60和90天复检患者粪便,发现其虫卵阴转率为97.50~100%。大部分患者自觉症状消失,一般情况明显好转,治疗副作用轻微而短暂。和其它药物的疗效和副作用相比,我们认为吡喹酮应成为治疗华支睾吸虫病的首选药物。通过与其他学者的研究比较,吡喹酮总剂量210mg/kg的3日疗法不亚于同剂量的5日疗法,因而获得满意的疗效。

【Abstract】 203 , cases of human Clonorchiasis were treated with praziquentel, by mouth in the total amount of 210 mg/kg three times a day for 3 days. The therapeutic results were evaluated 30, 60 and 90 days after the treatment. Clinical improvement and reduced egg counts were found to be noted. The negative rates were present in 95.5% to 100%. The side effects of praziquentel were mild and transient. We have the view that a larger total dosage of praziquentel for a 3-day course should be used to effect a cure.

  • 【文献出处】 蚌埠医学院学报 ,Journal of Bengbu Medical College , 编辑部邮箱 ,1987年03期
  • 【被引频次】3
  • 【下载频次】18
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