【摘要】 采用微量培养板的细胞病变抑制法,检测各种癌症病人血液中α—干扰素抑制物。共检测43份标本,其中含有干扰素抑制物的有28份,占65.12％;正常对照血清77份,仅26份阳性,占33.78％(T=2.31,P<0.05)二者有显著差别。鼻咽癌、宫颈癌、肠癌、肺癌病人血清的阳性率,分别为53.85％、62.50％、71.43％、85.71％。患者是否经过放疗与发病年龄对血清中干扰素抑制物的阳性率并无影响。结果提示,癌症患者体液内无干扰素抑制物,可能是患者接受干扰素治疗的前提。更多还原

【Abstract】 In this study, 43 samples of cancer serum were detected forinterferon inhibitor by microtiter CPE inhibition test. 28 samples of cancer serum were considered to be positive(65. 12 % ), however, in 77 samples of normal human serum there were only 26 samples to be positive(33. 78% ). This difference between cancer serum and normal human serum appeared to de statistical satisfactory(T=2.31, P<0.05). The samples of serum derived from noso-pharygeal cacinoma, cervical cancer,colon-rectal cancer, and lung cancer had positive rate of 53.85% 62.50%, 71.43%, and 85.71% respectively. The patients whether to receive radiotherapy or to be their ages did not influence to the positive rate of interferon inhibitor in their sera.The results showed that it is imperative that patient suffering from cancer whose serum had no interferon inhibitor could accept interferontherapy.更多还原