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中西医结合治疗流行性出血热休克的疗效观察

Observation on the Therapeatic Effect of Shock of 272 Epidemic Hemorrhagic Fever Patients Treated with TCM-WM

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【作者】 徐德先纵瑞森唐文轩钱茂林俊如王洪珠吴志红李韫华唐刚元王白英李梅霞张铭

【Author】 Xu Dexian Donghai County people’s Hospital,Jiangsu

【机构】 江苏省东海县人民医院江苏省东海县人民医院

【摘要】 作者对272例流行性出血热休克患者按中医辨证分为阴脱、阳脱和阴阳两脱三型。阴脱采用生脉散加味,阳脱方用参附汤加味,阴阳两脱则用参附龙牡救逆汤加味等中西医治疗方法。其休克纠正时间(20.3±4.2小时)较单纯西药治疗组(33.2±5.6小时)快,且血压反复率少(前者17.5%,后者67.6%)。治疗组病死率2.57%,而对照组16.18%,有非常显著差异(P<0.01)。

【Abstract】 272 cases of shock of hemorrhagic fever have been studied.Observation was made on clinical manifestation and laboratory findings.The main observation was made on the nail-fold microcirculation, the blood picture,the blood coagulation,the hemorrheological determinations and immunologic function tests.The patients were divided into two groups.One group was treated with combined therapy of TCM and WM,and the other group with WM exclusively,serving as control.The former group proved to be superior to the latter one,with better,therapeutic results and lower mortality. Several important points were discussed:(1)Decoction of Sheng Mai San(生脉散煎剂)was effective for emergency case of Yin Tuo(阴脱,exhaustion of Yin),while Shen Fu Decoction(参附 汤)was effective for emergency case of Yang Tuo(阳脱 exhaustion of Yang)too.(2)These two prescriptions possess cardiotonic and vasopressing function,and enhance the cell-mediated immunity. (3)Experiments showed that in patients with hemorrhagic fever,there existed stagnation in microcirculation.Salvia miltiorrhiza is important to promote the blood circulation and remove the blpod stasis.

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