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食用油加热产物的Ames试验

THE MUTAGENICITY OF PRODUCTS FROM HEATED OIL IN AMES TEST

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【作者】 瞿永华徐冠雄黄飞方君成高玉堂王蘅文

【Author】 Qu Young-hua

【机构】 上海市肿瘤研究所中国科学院上海细胞生物学研究所

【摘要】 <正> 吸烟与肺癌的关系,一般认为吸烟主要引起肺支气管鳞癌和未分化癌,而肺腺癌与吸烟的联系性很弱。根据本所流行病学研究室的结果,显示上海市女性肺癌中仅19.3%

【Abstract】 The mutagenicity of products from heated edible oil, rape-seed oil, refined rape-seedoil, soybean oil, peanut oil and lard, had been assayed with Ames test. The extracts ofcondensed volatiles of rapeseed oil, refined rapeseed oil, soybean oil heated at about 270℃were positive in tester strain TA98 which had been activated with S9, but negative withoutS9; that from peanut oil and lard could not increase the revertants of TA98 or TA100. Themutagenicity of extract from rapeseed oil volatilese was stronger than that from soybeanoil. All of these edible oil itself, heated or unheated, were negative neither in TA98 orTA100. The results provide an experimental clue for studying the possible relationshipbetween high proportion of lung adenocarcinoma in Chinese women and the habit ofChinese cooking-fry and stir at high temperature.

【基金】 中国科学院科学基金
  • 【被引频次】57
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