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404例舌癌放射治疗

RADIOTHERAPY FOR CANCER OF TONGUE

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【作者】 环素兰刘泰福

【Author】 Huan Su-lan et al

【机构】 上海医科大学附属肿瘤医院放疗科上海医科大学附属肿瘤医院放疗科

【摘要】 <正> 舌癌是头颈部常见的恶性肿瘤之一,在口腔癌中占32.3~50.6%,居首位。本院从1968~1975年共收治舌恶性肿瘤460例,其中舌鳞状细胞癌404例,随访至1981年底,28例失访,随访率93%。与手术相比,舌癌放射治疗的最大优点在于能保全说话和进食

【Abstract】 Four hundred and four cases of squamous carcinoma of tongue were treated withradiation at the Cancer Hospital of Shanghai Medical University from Jan. 1968 to Dec.1975, and 93% of cases were followed up for more than 5 years. Of the 404 cases, 368 hadlesions in the mobile portion of the tongue and 36 in the base of the tongue. The overall 5-year survival rate was 49.8%. 270 cases with lesions in the mobile portion of the tonguewere treated with external irradiation and interstitial radium implantation, 92 cases under-went simple external irradiation. The 5-year survival rate was 63.3% and 16.3% respec-tively. Invasion of the base of the mouth and metastasis to the lymph nodes were importantprognostic factors. Control of the primary carcinoma of the mobile portion of the tonguemay not only depend on dosage of interstitial radium, but also on total dosage of radio-therapy including external irradiation. Neck dissection is important in the treatment ofcarcinoma of tongue, 5-year survival rate of prophylactic and therapeutic neck dissectionis 85.7% and 62.0% respectively. For the cases without neck dissection,the 5-year survivalrate was only 36. 1%. Sixteen cases underwent salvage surgery due to failure in controllingthe primary or metastatic tumors by radiation, the 5-year survival rate was 43. 9%.

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