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消化道癌肿病人的血清铜锌水平及铜锌比值

Serum Copper and Zine Levels in Patients with Gastrointestinal Cancers

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【作者】 詹文华; 赵继宗; 王吉甫; 陈若娜; 曾小原; 李恺; 曾惠琳;

【Author】 Zhan Wenhua Zhao Jizhong Wang Jifu Chen RonoZeng Xiaoyuan Li Kai Zeng Hueilin (The Research Laboratory of Gastrointestinal Surgery)

【机构】 中山医科大学第一附属医院腹部外科研究室; 中山医科大学第一附属医院腹部外科研究室;

【摘要】 <正> 疾病情况下血清铜、锌水平的变化,已往研究多集中于何杰金氏病、白血病和肉瘤等,但结论不甚一致。少数作者报道了消化道恶性肿瘤时铜锌水平的变化。本文通过对消化道癌肿及某些良性疾患病人血清铜、锌浓度及铜锌比值的观察,试图评价其对这类疾病的临床实用意义。

【Abstract】 The Serum copper and zine levels were measured in 116 subjects. Among them 42 had gastrointestinal carcinoma including 22 large bowel cancer and 20 gastric and esopha-geal cancer; 43 had benign lesions, and 31 were normal. The serum copper level incleased significantly in the patients with gastrointestinal cancer and in those with benign lesions. The Cu Zn ratio was significantly higher in the patients with gastrointestinal cancer than those in the normal subjects and in the patients with benign lesions. It is concluded that in patients with gastrointestinal carcinoma, monitoring with serum copper concentration and copper/zinc ratio are of clinical value.

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