【摘要】 本文报道11例抑郁症患者的血清催乳素的测定,并以正常人20名及精神分裂症患者20例作为对照组,发现精神分裂症及抑郁症患者的血清PRL均较正常人为高。经统计处理,正常人与精神分裂症患者之间,或精神分裂症与抑郁症患者之间均无显著性差异(P>0.05),而发病期抑郁症患者与正常人之间却有显著性差异(P<0.05)。作者推测抑郁症患者的血清PRL增高可能是由于多巴胺的相应减少所致,值得进一步研究。更多还原

【Abstract】 The serum prolactin (PRL) levels were measured in 11 depressed patients, as compared with those of 20 normal subjects and 20 schizophrenics. The results showed that the serum prolactin levels of schizophrenics and depressives were higher than those of normal subjects,but the difference of the results between normal subjects and schizophrenics, or schizophrenics and depressives was not signifleant(P>0.05). However there was a significant difference between depressives in attack and normal subjects (P<0.05).The authers consider that the increased levels of serum PRL in depressed patients are probably due to relevant decrease of DA. Therefore, it is suggested that besides the 5-HT and NE Theories, the disturbunce of DA system may be related to the etiology and pathogenesis of depression. Further investigations are needed.更多还原