【摘要】 选择本省8个县、市已达消灭血吸虫病标准的18个村,应用COP和IHA对4361人进行调查。结果表明,距基本消灭血吸虫病10～15年的地区,人群的COP反应率和平均环沉率均降到与正常人相似的水平;因此,COP是考核消灭血吸虫病地区病情的一种可取的方法。但有血吸虫病病史者治疗后IHA的GMRT下降较慢,且仍较正常人为高,考核病情的应用价值较COP低。一个地区人群COP的平均环沉率与该地距基本消灭血吸虫病时间的长短和有血吸虫病病史人群所占比例间呈多元回归关系,根据三者间的多元回归方程,可得出COP平均环沉率的正常界值范围,为考核该地区是否达到消灭血吸虫病标准提供了参考数据。更多还原

【Abstract】 In 18 villages with schistosomiasis basically eradicated for 5 to 15 years and with proportions of cured patients ranged from 2.3% to 63.9%, a comparative study was performed between COP and IHA to see if they could be of use in the evaluation of disease control. A total number of 4 361 residents were examined and the results showed that in these villages with the disease controlled for more than 10 years the reaction rate and the mean oircumoval precipitin rate of the cohorts with past history were all similar to those without previous history of schistosomiasis, and those of the patients cured for more than 10 years were as low as those of the villagers without any history of the disease. However, the GMRT as well as the reaction rates of IHA in both cohorts in these villages differed significantly, and so did the 2 patient groups cured for more or less than 10 years.A relationship of multiple regression was presented among the mean circumoval precipitin rate of COP, the number of years for a successful basic eradication of thedisease (X1) and the rate of population with past history of schistosomiasis (x2) inthe given areas. The equation of the regression is Y=- 0.0198X1+ 0.0030x2+0.2744.This equation can be used to express the range of eradication of the disease after COP survey in an unknown area.更多还原