【摘要】 为了探讨日本棘隙吸虫病的治疗药物与方案,我们对50例粪检阳性病例采用吡喹酮进行治疗观察。50例分层随机抽样分为3组,分别给予吡喹酮20、10、5mg/kg顿服,各15、17和17例,另2mg/kg1例。上述3组治后1月粪检阴转率依次为86.7％(13/15)、94.1％(16/17)和100％(17/17):经统计学处理,3组间无显著差异(P>0.05)。2mg/kg者治后1月粪检仍阳性,但大便虫卵较治前减少94.4％。结果表明,吡喹酮是治疗该病的有效药物,药物副作用较轻,疗效较好,给药简便。建议在实际应用中采用5～10mg/kg顿服进行治疗。更多还原

【Abstract】 Pyquiton was given in a single dose of 20, 10 and 5mg/kg to 15, 17 and 17 patients with Echinochasmus japonicus infection respectively. 7-10 days after treatment the cure rates of the treated groups were 93.3%, 94.1% and 100% respectively. After 1 month, the cure rates were 86.7%, 94.1% and 100%. In addition, one patient who was given a single dose of 2mg/kg was found egg negative 7-10 days after treatment but became egg positive after one month. The drug was well tolerated. The preliminary results showed that pyquiton was highly effective with mild side effects in the treatment of Echinochasmus japonicus infection.更多还原