【摘要】 胶质瘤碱性蛋白免疫核糖核酸治疗103例脑瘤,计胶质瘤93例、脑膜瘤5例、松果体瘤、垂体瘤、多发性神经纤维瘤及转移瘤各1例。近期疗效,好转46例(44.6％),不变53例(51.5％),恶化4例(3.9％),典型病例于CT上见到肿瘤缩小、消失。比较55例天幕上恶性胶质瘤的远期疗效,iRNA加手术放疗的30例为治疗组,手术放疗的25例为对照组,2年存活率:治疗组为66.7％,对照组为28.0％,死亡病例的平均生存期,治疗组为13.1±2.28月,对照组为9.5±4.9月,有明显统计学意义。更多还原

【Abstract】 103 cases of brain tumor(glioma 93, meningioma 5, pinealoma 1, pituitary adenoma 1, metastatic carcinoma 1, neurofibromatosis 1) were treated by GBP immune RNA. 46 cases (44.6％) improved; 53 cases (51.5％) unchanged, 4 cases (3.9％) became worse. Some cases showed dramatic results. The tumor became shrinking or disappeared in CT scan. 55 cases of supratentorial malignant glioma were divided to two groups: (1) the first group consisted of 30 cases treating with iRNA plus surgical and radiotherapy; (2) the 2nd group included 25 cases treating with surgical and radiotherapy only. Two years survival rate in the first group Was 66.7％, while in the 2nd group Was 28.0％. The mean survival time of the died cases in the first group Was 13.1±2.28 months, in the 2nd group Was 9.5±4.9 months (p<0.01).更多还原