【摘要】 对79例糖尿病肾病患者分组进行治疗,在糖尿病治疗的基础上,分别给予口服丹参和潘生丁,观察其疗效。结果各组治疗后空腹血糖均明显降低,C_er明显升高,尿蛋白阳性率降低,但各组间治疗后空腹血糖下降值、C_er上升值和尿蛋白阳性率无显著差异,提示控制高血糖是改善糖尿病肾病的关键,可使早期肾脏功能损害得到明显改善。口服丹参和潘生丁在糖尿病肾病治疗中并不增强其疗效。控制高血压是防治糖尿病肾病的重要措施,有利于肾功能的改善。更多还原

【Abstract】 Treatment was carried out in 79 cases of diabetic nephropathy. On the basis of strict control of diabetes, Dipyrida-mole and Savia Miltiorrhizae (丹参) were given in 23 cases and 32 cases respectively, together with another 24 cases as a control group. In the groups with Dipyridamole and Savia Miltiorrhizae therapy fasting plasma glucose and urinary protein were decreased significantly and the creatinine clearance rate (Ccr) was increased. But the decrements of both fasting plasma glucose and urinary protein and the increment of Ccr showed no significant difference statistically as compared with the control group. It is essential to control the hyperglycemia, since the renal function can only be improved at the early stage of diabetic nephropathy when the hyperglycemia is well controlled. The drugs mentioned above did not improve the treatment. On the contrary, antihyperlensive therapy is important to improve the renal function.更多还原