【摘要】 本文报道22例不能切除的原发性肝癌行肝动脉插管化疗,其中6例配合肝动脉检塞,4例肝动脉结扎。临床分期Ⅱ期19例,Ⅲ期3例,动脉灌注药物6例单用乌头碱,4例单用5-Fu,l2例用乌头碱配合5-Fu治疗。治疗结果:治疗后中数生存期为6.6个月,3个月、半年和1年生存率分别为81.3％、50％、和13.6％。认为肝动脉插管化疗,特别配合肝动脉检塞或结扎是治疗不能切除的原发性肝癌的一种有效、安全的姑息疗法。更多还原

【Abstract】 A series of 22 cases of unresectable primary liver cancer seen from 1973 to 1985 and treated intra-arterially are reported. All cases were males. The ages ranged from 21 to 54. Nineteen patients were of clinical stage Ⅱ and 3 stage Ⅲ. Diagnoses were confirmed with histopathology in all but 2 cases which were verified by exploration and positive AFP. Infusion chemotherapy were given in 6 cases using aconitic base (Wutou), in 4 cases with 5-Fu, and in 12 cases with aconitic base plus 5-Fu. Survival rates at three-month, six-month, and one-year were 81.3%, 50%, 13.6% respectively. The authors believe that the intrahepatic arterial infusion chemotherapy, especially in combination with hepatic arterial ligation or hepatic arterial embolism is a safe and effective palliative treatment for unresectable primary liver cancer.更多还原