【摘要】 <正> 以往工作证明,电刺激猫的大脑皮层 SⅡ区使丘脑 CM 核神经元放电增加,使它们的伤害性反应减弱,这与电针对 CM 神经元的影响相类似。在 SⅡ区施加 GABA 后,电针对丘脑髓板内核群神经元伤害性反应的抑制效应被减弱。提示 SⅡ区对丘脑髓板内核群的下行性调节与针刺镇痛有关。更多还原

【Abstract】 Neurons in SII area of the cerebral cortex thatproject directly to the nucleus CM of the thalamuswere identified extracellularly by antidromic activa-tion.Eight neurons in SII were found to respond toelectrical stimulation of CM with invariant latencies,and to faithfully follow over 100 Hz stimulation in20 cats.The collision occured in 4 out of the 8neurons.Condition-test interaction was made in 2 ofthe 4 cortico-thalamic neurons.It was revealed thatthe conditioning stimulation could inhibit the nocice-ptive responses elicited by testing stimulation.Theinhibitory effect of elcetroacupuncture at "Zusanli"and "Huantiao" points on the nociceptive rcsponsesof the two neurons was also observed,The resultsindicate that electroacupuncture can activate the cor-tical neurons in SII projecting directly to the nuc-leus CM,which in turn yields descending modu-lation of its nociceptive afferents.更多还原