【摘要】 用国产乙型肝炎血源疫苗免疫HBsAg阳性产妇之新生儿。结果:HBsAg抗原血症之婴儿减少到6.52%(3/4)与对照组66.66%(28/42)对比,保护率为90.22%。婴儿产生抗—HBs的阳性率93.48%(43/46)与对照组对比,差异显著。更多还原

【Abstract】 Infants born of HBsAg carrier mothers were immunized by national HBva-ccine supplied by National Vaccine and Serum Institute, Beijing. The vaccine(lots of 81-2 and 83-1)was given to babies within 24 hr of birth and repeatedat 1, 2, and 6 mo. The results for 88 infants for 12 mo. indicate that thisvaccine is highly effications. Overall 3 of 46 vaccinated (6.52%)and 28 of 42controlled infants(66. 66%)were HBsAg pesitive at 6 mo. of age (P<0. 005, pro-tective efficacy 90. 22) .For infants born to eAg pesitive mothers 3 of 32 (9.39%)vaccinated and 22 of 24 (91.66%)controlled infants were HBsAg positive at 6mo.of age(P<0. 001, protective efficacy 89. 71%).更多还原