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三种含氯消毒剂对细菌杀灭作用的观察
OBSERVATION ON THE BACTERICIDAL EFFECT OF THREE CHLORINE-CONTAINING DISINFECTANTS
【摘要】 <正> 目前,含氯消毒剂仍不失为是一种高效、低毒、使用方便的好药。为了解灭肝宁-333、三氯异氰尿酸与甲醇次氯酸钠缓冲混合液等3种含氯消毒剂对细菌的杀灭作用,以作为实用中的参考,我们在实验室内进行了试验,现将结果报告于下。
【Abstract】 The killing effects of three chlorine-containing disinfectants on Escherichia coli and three kinds of bacterial spores were examined in laboraotory. Of the three disinfectants, trichloroisocyanuric acid showed most potent killing effect. It killed completely the spores of Bacillus cereus in suspension after 5 min contace at a concentration of 250 mg/L available chlorine (inactivation factor 10~8), sporg of Bacillus anthracoides and B. subtilis var. niger at a concentration of 500 mg/L available chlorine after a 15 min and 20 min contact respectively. Mixture of methanol, sodium hypochlorite and phosphate buffer (MSP)and solution of Miegannin 333 (a kind of organic chlorine disinfectant) at a concentration of 500 mg/L available chlorine gave an inactivation factor of 10~4~10~6 after a 20 min contact.When MSP and Miegannin-333 were used for killing Escherichia coli, solutions at a concentration of 12.5 mg/L available chlorine could kill 99.9% (inactivation factor 10~3) after a 15 min contact and those of 50 mg/L available chlorine could kill completely after 5 min (inactivation factor 10~8).Although trichloroisocyanuric acid showed strong bactericidal effect, its solution is unstable. The content of available chlorine decreased by 50% and 75% after standing for 24 hr and 7 days respectively at room temperature(16~18℃). On the contrary, the solutions of the other two disinfectants showed no change in concentration of available chlorine after standing for 7 days at room temperature.
- 【文献出处】 消毒与灭菌 , 编辑部邮箱 ,1986年04期
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