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几种消毒剂与抗菌素抗埃尔托弧菌作用的实验室观察

OBSERVATION ON BACTERICIDAL EFFECT OF SOME DISINFECTANTS AND ANTIBIOTICS AGAINST VIBRIO CHOLERAE BIOTYPE ELTOR IN LABORATORY

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【作者】 江智辉; 杨茂斌;

【Author】 Jiang Zhihui Yang Maobin (Anti-epidemic Station of Mianyang City, Sichuan Province)

【机构】 四川省绵阳市卫生防疫站; 四川省绵阳市卫生防疫站;

【摘要】 <正> 为研究对埃尔托弧菌感染的预防和治疗,在实验室内观察了一些消毒剂与抗菌素对该菌的杀灭或抑制作用。现将结果报告于下。

【Abstract】 The bactericidal efficacies of four disinfectants against Vibrio cholerae biotype eltor were estimated in laboratory. The results indicated that 0.1% peracetic acid or chlorine solution could completely kill the bacteria in suspension in 1 min, while an exposure time of longer than 3 minutes was required for complete kill when lysol or benzalkonium bromide solution at same concentration was used.Bacteriostatic test by paper disc method indicated that Vibrio cholerae biotype eltor was highly sensitive (the inhibition ring was larger than 25 mm in diameter) to medemycin, chloromycetin, streptomycin, doxycycline and kanamy- cin; moderately sensitive (inhibition ring was 20~24 mm in diameter) to pyridine carboxylie acid, tetracycline, erythromycin and terramycin; slightly sensitive (inhibition ring was 15~19 mm in diameter) to ampicillin, furazolidone, gentamycin and neomycin; and insensitive (inhibition ring was smaller than 15 mm in diameter) to aureomycin, penieillin and spiramycin. In China, doxycycline is the drug of first choice for clinical use at present time.

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