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乙型肝炎病毒感染标志在不同人群中分布和持续性感染标志的研究

The Distribution of the Marker of Hepatitis B Virus Infection in Different Populations and the Marker of Sustained Infection

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【作者】 丁正荣; 李一飞; 李荣成; 陈琨琳; 李艳萍; 龚健; 农远志; 冯永贞; 王福菊; 李燕超;

【Author】 Ding Zhengrong et al, Anti-epidemic Station of Guangxi Zhuangzu

【机构】 广西壮族自治区卫生防疫站肝炎研究室; 北京生物制品研究所; 隆安县防疫站; 南宁地区防疫站;

【摘要】 <正> 为探讨不同人群中乙型肝炎病毒(HBV)感染标志的分布特点,我们对原发性肝癌病人、急性肝炎、慢性活动性肝炎住院病人,以及肝癌高发区和低发区一般人群用固相放射免疫。法(RIA)检测HBV感染标志,并进行比较分析材料与方法一、研究对象原发性肝癌病人55例,均系隆安县医院诊断病例,经临床症状,体征及甲胎蛋白(AFP)检查确诊者。慢性活动性肝炎病人105例和急

【Abstract】 HBV infection marker was tested by RIA and ELISA in 55 cases of primary hepatic cell carcinoma, 105 cases of chronic active hepatitis, 211 cases of acute hepatitis, 1161 persons of the population at high risk of liver cancer and 822 persons of those at low risk of the cancer. It was found that the positive rate of HBsAg plus high titer of anti-HBc (RIA inhibition rate>80%) was highest in liver cancer cases (85.5%) and decreased successively in chronic hepatitis, acute hepatitis, population at high risk of liver carcinoma and those at low risk of the cancer. The positive rate of single anti-HBc aried in the opposite direction, being lowest in liver cancer patients.HBsAg plus high titer of anti-HBc could be considered as the marker of sustained hepatitis infection. Its positive rate was much higher in the population at high risk of liver cancer than those at low risk of the cancer. The high rate of sustained infection might be related to some promoting factors in the environment.

  • 【文献出处】 中国公共卫生 ,Chinese Journal of Public Health , 编辑部邮箱 ,1986年05期
  • 【被引频次】3
  • 【下载频次】27
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