【摘要】 <正> 地方性氟中毒的病因虽已清楚,但其发病机制尚未充分阐明。因此氟中毒特别是氟骨症的早期诊断问题一直是防治科研工作中急需解决的问题之一。目前,一般公认 X 线检查是确诊氟骨症唯一客观而可靠的依据,但实际上它属于晚期诊断。尿氟虽然可以做为评价群体水平的指标,对诊断有一定参考价值,但由于它受许多因素的影响,变异较大,对诊断个案病更多还原

【Abstract】 This report presents the resultsof the determination of 12 biochemi-cal indices of serum by usingMCA Blood Biochemistry Autoanaly-zer.The determination was madeon 87 cases of which 50 lived influorosis area and 37 in non-fluoro-sis area as control.The results show that the differen-ces are statistically significant on6 serum biochemical indices betweenthe cases of fluorosis area and thoseof the control area.They are Akp、LDH、uric acid、inorganic phospho-rus and calcium;Nevertheless,thereare no differences between the caseswith fluorosis x-ray manifestationand those with normal manifestationin the fluorosis area.Through discriminant analysis,adiscriminant function which includesfour variables such as AKP、LDH、uric acid and inorganic phosphorusof serum is established as follows:Z=-0.083641x₁+0.057906x₄+0.616904x₉-3.518981x₁₁,The contributionsare 24.35,15.26,30.11 and 30.29respectively and the discriminanteffect of this function is wellFrom these data mentioned above,it might be seen that detecting bio-chemical indices of serum might beof some significance for the earlydiagnosis of fluorosis.So it is nece-ssary to work on this subject further.更多还原