【摘要】 研究了中性抗坏血酸注射液在无氧条件下的降解产物和降解反应。检测出的降解产物有;2-酮-L-古洛糖酸、二氧化碳和木糖,分离、鉴定了新的降解产物——丙酮醛,并研究了抗坏血酸的水解与2-酮-L-古洛糖酸脱羧的反应动力学,提出了中性抗坏血酸注射液在无氧条件下可能的降解途径。更多还原

【Abstract】 The anaerobic degradation of ascorbic acid in neutral injection has been studied. Some degradation products as 2-keto-L-gulonic acid and xylose were identified by using of TLC. A new degradation product pyruvaldehyde was isolated and identified as 2,4-dinitrophenylhydrazone. The amount, of 2-keto-L-gulonic acid formed from degradation of ascorbic acid in injection and amount of carbon dioxide produced from that of ascorbic acid and 2-keto-L-gulonic acid were determined. From these, the pathway for the anaerobic degradation of ascorbic acid in neutral injection Was proposed.更多还原