【摘要】 <正> 姜黄为姜料植物Curcuma longa L.的根茎,为一常用中药。近年来用于治疗高脂血症有较好疗效,且无毒副作用。其主要化学成分为姜黄素、去甲氧基姜黄素及二去甲氧基姜黄素。实验证实姜黄素为其降血脂的主要有效成分。姜黄素类化合物过去多采用在420 nm附近测定黄色素的方法,此类方法不够稳定,易受其它黄色素的干扰。利用姜黄素与硼生成红色络合物而进行测定,比较专一而灵敏。对更多还原

【Abstract】 A high performance liquid chromatographic method for the separation and determination of curcumin, demethoxycurcumin and bisdemethoxycurcumin in Curcuma longa L, and its preparation is reported in thispaper. Determination was carried outunder the following conditions: column: YWG-C₁₈H₃₅, 10 μm 200×4.6 mm; N （naphtha-lene） =40000/m; eluant: THF—H₂O—glacial HOAc （36:58:6, V/V/V）; pressure: 110 kg/cm²; flow rate: 1 ml/min; paper rate: 5mm/min; UV-254 nm; naphthalene was used as an internal standard. This method is quick and simple, and other yellow soluble substance of Curcuma longa L. did not interfere. Four crude drug samples obtained from Guangdong, Jiangxi and Sichuan, total curcuminoid extract and curcuminoid capsula were determined with satisfactory results.更多还原