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小叶地不容生物碱的研究
ALKALOIDS FROM STEPHANIA SUCCIFERA H. S. LO ET Y-TSOONG
【摘要】 <正> 小叶地不容(Stephania succifera H.S.Lo et Y-Tsoong)为防己科千金藤属植物,产于海南岛。该属植物在我国分布很广,不少可作药用,有消炎、镇痛等作用。小叶地不容的化学成分尚未见报道。我们采用离子交换法提取总碱,自乙醚洗脱部分分得八种生物碱。碱Ⅰ、Ⅱ、Ⅲ、Ⅳ和Ⅷ的物理常数和光谱数据分别与文献报道去氢克班宁(dehydrocrebanine)、1-四氢巴马亭、克班宁(crebanine)、schefferine和asimilobine的
【Abstract】 Eight alkaloids were isolated from Stephania succifera H. S. Lo et Y-Ts0ong. Alkaioids Ⅰ, Ⅱ, Ⅲ, Ⅳ and Ⅷ were identified as dehydrocrebanine, (1)-tetrahydropalmatine, crebanine, schefferine and asimilobine respectively. Schefferine, and asimilobine were first reported to occur in Stephania genus. Alkaloid Ⅶ was shown to be crebanine N- oxide on the basis of spectroscopic dataand chemical evidence. The structure elucidation of alkaloids Ⅴ and Ⅵ is still underway.
- 【文献出处】 药学学报 ,Acta Pharmaceutica Sinica , 编辑部邮箱 ,1986年03期
- 【被引频次】11
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