【摘要】 作者采用骨髓细胞短期培养和热变性姬姆萨 R 显带技术(RHG),对17例急性非淋巴细胞白血病进行染色体检查,发现88%的病例有克隆性核型异常,并揭示数种非随机的改变。本研究结果明显优于作者过去用 G 显带的结果。表明 RHG 是一种较好的显带技术,对白血病的染色体研究尤为适用。更多还原

【Abstract】 Cytogenetic studies were successfully performed in 17 patients(8 males,9 females, aged 9～56 years)suffering from acute nonlymphocytic leukemia at presentation using of short term cultures of bone marrow cells and the R-banding technique.Abnormal clones were derected in 15 cases(88%).Some of these were non randoms:t(8;21)in two cases with M2 subtype,t(15;17)in all six cases with M3 subtype,abnormalities involving chromosome 11 in three cases with M5 subtype. The results obtained by this R-banding method in chromosome study of leukemia were much more preferable to our former old G-banding technique.更多还原