【摘要】 58例HBsAg 无症状携带者第7～12年的动态变化研究结果表明,48.28%仍为持续稳定的无症状携带者,仅10%其HBsAg 阴转或康复;24人在携带过程中出现肝功能异常,发生急性肝炎,其中14人预后良好,成为病后携带者;10人发生急性肝炎后,发展为迁肝、慢活肝。平均每年有5.91%的携带者发展成各型临床肝炎。凡有过HBsAg 阳性、慢迁肝病人或抗-HBcIgM 滴度≥1:100者,Dane 颗粒检出率均高(63.64%,70.00%,44.00%),三者检出率在统计学上无显著性差异(P>0.05),均有较强的传染性;因此在乙型肝炎防治工作中应列为重点对象。更多还原

【Abstract】 58 asymptomatic HBsAg carriers were studied on follow-up for 7～12 years.It showedthat 48.3% of patients were still being persistent carriers,and 10% became HBsAg-negativeor recovered.24 carriers had developed acute hepatitis with abnormal liver function,and14 of them clinically recovered in spite of being the carriers the same,while the remaining10 carriers turned to be eases of acute hepatitis,persistent hepatitis and chronic activehepatitis.Thus the annual recurrence rate of hepatitis in carriers averaged to be 5.9%.The prevalence rates of Dane’s particles were found to be high in three conditions,which were patients having been HBeAg positive (63.6%),patients with chronic activehepatitis(70%),and the patients with titer of anti-HBcIgM≥1∶100(44%).No significantstatistical difference among these 3 figures (p>0.05),however the infectivity of thesecarriers were all high.Therefore watchful control of hepatitis B in these 3 groups ofcarriers should be warranted.更多还原