【摘要】 <正> 灵芝对实验性严重烫伤性休克具有较好的保护作用;并对休克大鼠的心肌线粒体亦有保护作用;它还能降低耗氧量、增加红细胞和血红蛋白的含量,并能提高血浆和心肌组织中的cAM P 的水平。为了进一步探讨和发掘灵芝的其他药理作用,特设计制备胰腺微循环障碍的病理模型,用以检验灵芝对重要内脏微循环有何影响。更多还原

【Abstract】 The 45 rats were divided into 2 groups randomly.After giving10% high-viscosity dextran 4 ml/kg body-weight intravenously.Plasmaviscosity & red-cell aggregation increased,aggregation & stasis ofcell in the capillaries and significant decrease in the speed of bloodflow could be seen under microscope.The models of microcirculatirydisorder of rats pancreas have formed.Drug activities can be evaluated according to the 4 indexes:states of blood flow:speed of blood flow;points of interlace of blood vessels & colour of blood.The intravenous administration of 108 mg/kg body-weight ofGanodema extractive resulted in a significant acceleration of bloodflow,& increasing points of interlase of blood vessels & band-shapedblood flow from granular-shap.The result suggestes that this Chinese medicinal herb is effectivein improving microcirculation of pancreas.更多还原