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空气负离子对γ-射线诱发小鼠染色体畸变和SCE防护作用的研究

Studies of Air Negative Ion Protection from the Chromosome Aberrations and SCEs Induced by γ-rays in Mice

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【作者】 郭学聪刘凌云刘彦狄少杰费青周瑞英谢林郭玥

【Author】 Guo Xuecong Liu Lingyun Liu Yan Di Shaojie Fei Qing(Department of Biology,Beijing Normal University)Zhou Ruiying Xie Lin Guo Yue(The Inititute of Low Energy Nucltar Physics,Beijing Normal University)

【机构】 北京师范大学生物系北京师范大学低能核物理研究所北京师范大学低能核物理研究所

【摘要】 鉴于空气负离子对医疗保健有良好效应,而对染色体和DNA起什么作用尚缺乏研究,要直接研究空气负离子对染色体DNA的作用较为困难,因此,本文试图通过辐射效应探索空气负离子的作用。应用空气负离子处理昆明小白鼠70天,再用γ-射线照射动物。辐照后分9个不同时间取样,分析小鼠骨髓细胞染色体畸变和SCE等的变化。结果表明空气负离子对辐射诱变具有防护作用。

【Abstract】 In view of the fact that the air negative ions have good effect on medical treatment and health,we consider it rather difficult to study directly about the effect of the air negative ions on the chromosomes and DNA.It has been known that the DNA is an important target molecule of radiation,so this paper presents an exploration through the effect of radiation to see whether the air negative ions would protect the chromosomes and DNA from radiation damage.The Kunming mice were used as the experimental animals (male,average body weight: ca.12g).According to the same degree of body weight,the 302 mice were divided into six cages at random.These mice were reared in two rooms built in the same style.Three cages of mice were put in one room provided with the air negative ions,while the other three were put in the other room provided with the same amount of the ordinary air as the air negative ions.In doing so 70 days running,these mice were exposed to γ-rays.After radiation they were killed at 2,4,8,12,16,20,24,36,and 48 h respectively,and their bone marrow cells were used to make the chromosome preparations,then various aberrations and SCEs of chromosomes and chromatids were examined under microscope and statistical analysis was made.The experimental data showed that there is a protective function of air negative ions on the chromosome damage induced by radiation.

  • 【文献出处】 遗传学报 ,Acta Genetica Sinica , 编辑部邮箱 ,1986年06期
  • 【被引频次】3
  • 【下载频次】36
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