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新药丙氧咪唑驱治肠道线虫效果观察

CLINICIAL TRAILS WITH OXIBENDAZOLE FOR INTESTINAL NEMATODE INFECTIONS

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【作者】 吴中兴陈有贵郑葵阳祝惠民戴梅秀朱永昌蒋炳江闵琦李峰钟传新

【Author】 Wu Zhongxing, et al (Department of parasitology, Xuzhou Medical College, Jiangsu)

【机构】 徐州医学院徐州铁路卫生防疫站徐州铁路卫生防疫站

【摘要】 新药丙氧咪唑驱治肠道线虫感染,剂量用15mg/k9顿服,连用3天,钩虫卵阴转率分别为84.6%(片剂)和75%(胶囊),蛔虫卵阴转率为92.85%,对两种钩虫有同样疗效,副作用轻微、暂短。

【Abstract】 The newly synthesized anthelminthic, Oxibendazole, was used to treat 114 patients with nematode infections on an oral dose 15 mg/kg per day for 3 successive days. Results showed that the negative conversion rates of hookworm eggs were 84.6% and 75% for tablet and capsule respectively (p>0.05); those of ascaris and whipworm eggs were 92.85% and 83.3% respectively.The drug wrs equally efficacious for both Ancylostoma duodenale and Necator americanus. Its side reactions were mild and transient.

  • 【文献出处】 徐州医学院学报 ,Acta Academiae Medicinae Xuzhou , 编辑部邮箱 ,1986年04期
  • 【被引频次】8
  • 【下载频次】20
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