【摘要】 羟基哌喹治疗尘肺163例,主要症状改善率为44.04～77.78%;X线胸片显示好转,占9.76～13.11%,稳定占80.33～80.48%,有进展者占6.56～9.76%;长期用药未发现严重副作用。认为羟基哌喹有减轻症状,阻止或延缓病程的作用。可推荐应用治疗尘肺。更多还原

【Abstract】 The clinical cfficacy and side effects of Hydroxypiperaquine have been observed in 163 pneumoconiosis patients. The results showed that the improvement rate of the major symptoms was 44.01～77.78%. Chest radiograph reveals that 9.76～13.11% of patients were improved, 80.33～80.48% stable and only 6.56～9.76% in progress. The rates of progress during five years before or after tre atment was 58.54% and 9.76% respectively. The rate of progress was 84.62% in the control group and 15.38% in the therapeutic group.No serious side effects was found during treatment. This study proved that hydroxypiperaquine can alleviate patients’ suffering, inhibit or retard the progress of the disease. It is recommended that the hydroxypiperaquine can be used as a better drug for pneumocontosis treatment.更多还原