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联苯双酯治疗慢性肝炎的疗效观察

Observation on therapeutic efficiency of BDD in chronic hepatitis

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【作者】 王克欣倪承瑞胡爱兰余润玉

【Author】 WANG Ke-xin, NEI Cheng-re,HU Ai-lan, YU Run-yu. (Beijing Second Infectious Disease Hospital, Beijing 100054)

【机构】 北京第二传染病院北京第二传染病院 北京 100050北京 100050北京 100050

【摘要】 采用联苯双酯治疗慢性肝炎24例,其中慢性活动性肝炎21例,慢性迁延性肝炎1例,肝硬化2例。以甘草甜素组作为对照。治疗组在治疗后GPT的平均值逐渐下降,对照组下降不明显。治疗8wk(周)总有效率,治疗组为88%,对照组为68%,经统计学处理两组有显著差异。对TTT,血清蛋白的疗效不满意。

【Abstract】 Biphenyl Dimethyl Dicar-boxylate (BDD) was used in 24 cases of chronic hepatitis. Among them, chronic active hepatitis 21 cases, chronic persistent hepatitis 1 case, hepatic cirrhosis 2 cases with Stronger Neo-minophagan -C (SNMC)as control. During the treatment with BDD, the average level of GPT was decreased gradually and predominantly. But no prominent effect was seen in control .After 8-week therapy, the total ef-fective rate was 87.5% (BDD group), and 68% (SNMC group) . There is statistical significance between the 2 groups. In HDD group, however, improvement ol TTT and serum protein was unsatisfactory .

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