【摘要】 PVA（聚乙烯醇）—PEG（聚乙二醇）烧伤治疗膜的急性毒性实验未测出 LD₅₀,皮下注射150ml/kg 死亡率仅40%。亚急性毒性实验肾功能明显下降,肾小球内有淡兰色异物。短期皮下注射停药30天后肾小球内异物消失。烫伤实验肾小球内未见异物,说明形成膜覆盖于受损皮肤表面不易吸收。为一种安全的外用膜剂。更多还原

【Abstract】 The LD₅₀ of PVA（Polyvinyl alcohol）-PEG（Polyglycol）membra- ne for treating burn Could not de- temined by acute toxic experiment, bacuse mortality was only 40% with 150ml/kg i·P.Subacute toxic expe- riment showed that renal function depressed,and the blue foreign body existed in tne glomerule.If we had used hypodermic injection for short term,the foreign body in the glom- erule would have eliminated after withdrawn administration in 30d, In burned experiment,we observed not the foreign body in the glome- rule.It suggested the Compounds covering on the face of Injuried skin wasn’t easy absorbed.It is a safe external using Preparation of the medicinal membrane.更多还原