【摘要】 本题总结了100例感染过敏性关节炎的多抗甲素治疗及其病因学探讨的结果。随访观察六个月至四年,多抗甲素组(100例)治愈率84%;安慰剂对照组(20例)5%减轻,两组比较结果,P<0.005。并观测HLA20例、HLAB-7抗原阳性者55%,与对照组(7.14%)相比较,P<0.005,有统计学意义。本题探讨结果表明,多抗甲素具育抗炎、抗过敏、鉴别小儿生长痛和佐证说明本病病因学的作用。更多还原

【Abstract】 This paper summarizes the results the treatment of 100 cases with infectious allergic arthritis with alpha-Polyantigen and its etiologic analysis. After treatment in 90.48% of patients the joints swelling and pain subsided in 1-10 days; ESR, alpha-2, gama-globulin, C-3 decreased ( p < 0.001 ); ASO and CIC decreased (respectively P < 0.05 and 0.005 ); serum electrophoresi A and IgA increased (respectively p < 0.001 and 0.005). After 6 months to 4 years of follow-up the cure rate for the alpha-Polyantigen group (100 cases )was 84%, as compared with the placebo group ( 20 cases ) in which 95% of cases did not respond ( p < 0.05 ), with the Chloroquine-Tndocin group ( cure rate: 60.67% p < 0.005 ) and with the tonsillecto- mic group(cure rate: 37.5%; p<0.005). According to HLA in 20 cases there were 55% of cases with positive HLA-B-7 antigen, as compared with the control group ( 7.14%; p < 0.005) , howing that there is significant difference. The results show that alpha-polyantigen has nti-inflammatory and anti-allergic actions, by which the diagnosis of child growth-pain can be made and the etiology of the disease explored.更多还原