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原发性高血压肾素、血管紧张素Ⅱ分型及其相互关系的探讨
Classification and Correlation of Renin and Angiotensin in Primary Hypertension
【摘要】 <正> 为了进一步探讨血浆肾素活性(PRA)和血管紧张素Ⅱ(ATⅡ)浓度之间及其与血、尿中钠、钾的关系,并探讨原发性高血压肾素分型变化规律,我们对已进行调查研
【Abstract】 Two hundred and seventy-six patients with essential hypertension observed 1~1.5 years before had randomly reexamined 113 of them with the same items andmethods.Comparative analysis was made as follows:1.According to PRA and ATII typing,the results of the first and the secondexamination were compared.The stabilities were higher in the normal types(68.3%and 60.8% respectively).In evaluating the types of indiviual patient among the 113 cases,12 cases areboth normal,1 case is of high type and 1 case is of low type.The total stabilityrate is 12.4%.We conclude that typing by a single index,whether PRA or ATII,islimited in clinical use.2.Twenty-four hours urinary sodium excretion is lower and the potassium excre-tion is higher than that of the normal control group in the first examination theyreturn to normal in the second examination.This changes might be related to thetreatment during the period of 1~1.5 years.3.Correlation between PRA and ATII in patients group is positive(r=0.2564,P<0.005)in the first exmination,but no correlation in the second examination(r=0.041,P>0.005)which is similar to the normal control group(r=0.079,P>0.05).
- 【文献出处】 天津医药 ,Tianjin Medical Journal , 编辑部邮箱 ,1986年01期
- 【被引频次】2
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