节点文献
用ABC方法研究两种小鼠白血病分型
TYPING STUDY OF TWO MODELS OF MICE LEUKEMIA BY THE ABC METHOD
【摘要】 本文通过卵白素生物素复合物(简称ABC)免疫组织化学的方法标记Thy1、2,Lyt-1,Lyt-2和Iak~2四种单克隆抗体,研究了L7712和P388两种小鼠白血病模型的免疫学分型。实验结果提示L7712属于抑制性T淋巴细胞性白血病,P388属于B淋巴细胞性白血病。
【Abstract】 The immunohistoohemical characteristics of leukemia in mice were inve stigatd with monoclonal antibodies Thy1,2, Lyt-1, Lyt-2 , and Iak2 using the ABC immunological method. Results showed that all the tumor cells from L 7712 were strongly positive for Thyl, 2 and Lyt-2 and negative for Lyt-1 and Iak2 indicating their origin from suppressor T-lymphqcyte. All the tumor cells from P388 were strongly positive for Iak2 and negative for Thyl, 2, Lyt-1 and Lyt-2 indicating their origin from the B-lymphocyte and not T-lymphocyte. Other related data are discussed.
【关键词】 小鼠白血病;
T淋巴细胞;
B淋巴细胞;
单克隆抗体;
ABC免疫组织化学方法;
【Key words】 mouse leukemia; T-lymphocyte; B-lymphocyte; monoclonal antibody; ABC immunohistochemieal method;
【Key words】 mouse leukemia; T-lymphocyte; B-lymphocyte; monoclonal antibody; ABC immunohistochemieal method;
- 【文献出处】 上海医科大学学报 , 编辑部邮箱 ,1986年04期
- 【被引频次】3
- 【下载频次】13