【摘要】 本文报道用原子吸收法对20例胃癌和20例萎缩性胃炎患者血清、头发、胃粘膜活检组织中锌、铜和铁含量的测定结果,并与对照组进行比较。结果:与萎缩性胃炎组和对照组相比,胃癌组血清锌降低,而血清铜和血清铜/锌比值升高。胃癌组和萎缩性胃炎组血清铁和头发锌均低于对照组。胃粘膜活检组织中锌、铜、铁含量差别无统计学意义。对胃癌、萎缩性胃炎与锌、铜、铁含量变化的因果关系和临床意义进行了讨论。更多还原

【Abstract】 Zinc, copper and iron concentration in serum, hair and gastric biopsy specimens of 20 patients with gastric cancer and 20 patients with atrophic gastritis were measured by atomic absorption spectrophotometer and graphite furnace. The results are as follows:1. In patients with gastric cancer, the serum zinc concentration is lower, while the serum copper concentration and the copper/zinc ratio are significantly higher as compared with those in atrophic gastritis and normal controls.2. The serum iron concentration decreases significantly in both gastric cancer and atrophic gastritis.3. The hair zinc concentration is significantly lower in both patients with gastric cancer and atrophic gastritis than that in normal controls.4. Both the average zinc and copper concentration in gastric biopsy specimens are ranked in following sequence: atrophic gastritis < gastric cancer tissue < tissue surrounding gastric cancer < normal controls, but without statistical significance.更多还原