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糖尿病患者的血清脂类与载脂蛋白B和C

PLASMA LIPIDS AND APOLIPOPROTEIN B, C IN DIABETES MELLITUS

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【作者】 徐松德王明运吴湘云邓景惕刘贤锡罗道春张春玲

【Author】 Xu Songde (Dept.of Biochemistry, Shandong Medical University)

【机构】 山东医科大学生物化学教研室山东医科大学生物化学教研室山东医科大学附属医院内科

【摘要】 测定了42例糖尿病患者与27例健康者的血浆脂类、脂蛋白及载脂蛋白水平,结果:糖尿病患者的TG、TCh、LDL-Ch、HDL3-Ch及Apo B均高于对照组,HDL-Ch和Apo CⅡ低于对照组,表明糖尿病患者血浆脂类、载脂蛋白代谢异常,容易发生动脉粥样硬化。

【Abstract】 The levels of plasma lipids and apolipoprotein B, C of 42 diabeties (23 cases for type Ⅰ and 19 cases for type Ⅱ ) and that of 27 healthy peoples have been determined.Serum TG TCh LDL-Ch HDL3-Ch and Apo B concentration are significantly increased and the serum HDL-Ch and Apo CⅡ levels are significantly decreased in diabetes mellitus.The results reflect that the disorder of metabolism of lipids and apolipoprotein is serious in diabetes mellitus, particularly in type Ⅱ .It also suggests that diabetes mellitus promote the development of coronary artery disease.

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