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胰岛素滴鼻剂对正常家兔降血糖作用的研究

A STUDY ON THE HYPOGLYCAEMIC EFFECT OF NASAL DROPS OF INSULIN ON NORMAL RABBITS

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【作者】 陈文缘; 王清纯;

【Author】 Chen Wenyuan et al Department of Biochemistry Luzhou Medical College

【机构】 沪州医学院生化教研室; 沪州医学院生化教研室;

【摘要】 由非离子型表面活性剂Brij58、硬脂酸和结晶胰岛素所制成的滴鼻剂,滴入家兔鼻腔后,在不同时间测定其血糖浓度的变化。实验结果表明:滴药后30分钟出现血糖浓度的降低,60分钟达最低值,降血糖效应持续二小时以上。

【Abstract】 Naristillae (nasal drops) consists of Brij 58, stearic acid and crystalline insulin. It was dripped into tile nasal cavities of a group of rabbits, and then their blood sugar concentrations were determined at regular intervals. A reduction in the blood sugar concentration was observed 30 minutes after the administration and the lowest value was reached in 60 minutes. The hypoglycaemic effect lasted over two hours.

【关键词】 胰岛素; 投药; 鼻内; 血糖; 兔;
【Key words】 Insulin; Administration; intranasal; Blood glucose; Rabbits;
  • 【文献出处】 泸州医学院学报 ,Journal of Luzhou Medical College , 编辑部邮箱 ,1986年04期
  • 【被引频次】3
  • 【下载频次】39
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