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异源肠球菌定居的初步探讨

A PRELIMINARY STUDY ON COLONIZATION OF HETEROGENOUS ORIGIN ENTEROCOCCI

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【作者】 王晓春; 廖延雄;

【Author】 Wang Xiao-chun and Liao Yen-shyong(Postgraduate) (Major professor)(Microbiological Institute,Jiangxi Academy of Sciences)

【机构】 江西省科学院微生物所; 江西省科学院微生物所 研究生; 导师;

【摘要】 来自正常婴儿的运动链球菌(C48),能运动,有别于其它一般的肠球菌;不发酵甘露醇,有别于其它来源的运动链球菌.利用抗菌素清除正常成年小白鼠和刚出壳的罗斯雏鸡胃肠道正常菌群,然后灌服C48lml(108/ml),定期、定量观察检查小白鼠和罗斯雏鸡的胃肠道菌群的变化.实验结果表明:来自正常婴儿的运动链球菌能长期定植寄居正常小白鼠.C48与小白鼠之间有其生态平衡的条件,但存在着个体差异.在胃肠道正常菌群紊乱的条件下,C48可能有致病意义.C48亦能够在雏鸡消化道中定居,但结果有所不同.

【Abstract】 A motile stretococcus (C48) from a normal infant was differentiated from other enterococci by motility and from other motile enterococci by not fermenting mannose. The normal intestinal bacteria of conventional ’mice, and 1-day-old Ros chickens were eliminated by antibiotics. Then about 1 ml (108/ml) C48 was given per os. Changes of intestinal enterococcus flora were determinated at various intervals. Colonization test manifested that the motile enterococci C18 from the normal infant could colonizate a long period up to sixty days or more in conventional mice intestine. There was an ecologic balance of C48 in mice intestine. But the degree of colonization was variable with different individuals.Under disorder condition,as C43 muliplied too much in the intestine,C48 could cause disease. C48 could colonizate in younger chicken intestine too, but the result of chicken was somewhat different from that of mice.

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