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人胚胎主动脉组织结构的胎龄性变化

HISTOLOGICAL ALTERATION OF AORTA OF HUMAN EMBRYO

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【作者】 李秀芝; 严悦卿; 龙治峰; 杨永宗; 李植标; 金海燕;

【Author】 Li Xiuzhi Department of Histoembryo

【机构】 衡阳医学院组胚教研室; 衡阳医学院组胚教研室; 衡阳医学院心血管病研究室;

【摘要】 为了解动脉粥样硬化的组织发生,观察了224例不同胎龄的胚胎主动脉的结构变化:第二个月,单层内皮紧贴内弹性膜;中膜薄,细小弹性纤维联络成网,其中可见未分化的平滑肌细胞。第三个月可见内皮下层,内弹性膜出现窗孔。第四个月,内弹性膜分层现象普遍出现;平滑肌细胞的排列形似中膜通过内弹性膜窗孔游走进入内膜。文章讨论了所得结果的理论意义。

【Abstract】 In order to understand the tissue development of atherosclerosis, we observed the structure alteration of the aortic wall in 224 cases of embryo with different periods in embryonic life(2—10 months). In the second month of life, a layer endothelium was intimately adherent to the internal elastic lamina. The media was thin and there were undifferentiated smooth muscle cells in the network of fine elastic fibers, in the third month, subendothelial layer was observed and the internal elastic lamina had fenetration. The internal elastic membrane divided to several layers in the period of fourth month, it could be seen that the smooth muscle cells were oriented as if migrating from the media through the fenetrations of the internal elastic lamina into the intima. The theoritieal significances of the results observed are discussed.

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