【摘要】 从423例经RPHA确定为HBsAg阴性的献血员中,再用HBsAg-抗-HBs固相放射免疫双测定药盒复查,证实有15例(3.5％)献血员携带 HBsAg。用被动血凝抑制试验检测抗-HBc,发现 304例献血员中,有101例(33.2％)血清中含抗-HBc(滴度>1:100),其中有 8例(7.9％)HBsAg和抗-HBc同时为阳性。作者认为在筛选献血员时,应该用放射免疫等敏感性高的技术检测HBsAg,同时最好能辅以检测抗-HBc,以减少输血后肝炎。更多还原

【Abstract】 Sera of 423 voluntary blood donorswere collected and found to be negativefor HBsAg by reverse passive haemag-glutination (RPHA).However,whenthese sera were retested by solid phaseradioimmuno - two - assay kit of HBsAg andanti-HBs (SPRIA),15(3.5%) were positivefor HBsAg.Also,all of 304 bloodsamples from blood donors were testedfor the presence of anti-HBc by immuneadherence haemagglutination inhbition, thepositive rate(anti-HBc titre>1:100)was 33.2%(101).Among these sera,8(7.9%) samplescontained both HBsAg and anti-HBc.Thisstudy emphasizes the fact that RPHA testalone is not good enough to screenblood donors and that voluntary blooddonors should be carefully screened byusing more sensitive rests so as toimprove the quality of donated bloodand prevent HBV infection and post-transfusion hepatitis.更多还原