【摘要】 本文报道一例肺孢子虫肺炎的尸解材料,着重讨论了本病的组织病理学特征、诊断和鉴别诊断,并对渗出物的形成机理略加讨论。更多还原

【Abstract】 This paper presents an autopsy case ofpneumocystis pneumonia. The patient wasa 4-month-old infant, with a slowly increas-ing nonproductive cough, dyspnea, cyano-sis and mild fever. The X-ray chest filmshowed irregular ill-defined. patch opacitiesin both lung fields. After 13 days hospi-talization he died of respiratory failure. Postomortem examination revealed that?oth lungs had been enlarged with wide-spread greyish-yellow consclidations resem-bling those of confluent lobular pneumonia.Microscopically, most of the alveoli becamedistend d and filled with eo inophilic granu-lar protein exudate with sparse macropha-ges, and only a few of the alveoli were filledwith characteristic foamy amorphous con-tents. PAS and Grocott’s methenaminesilver stainings revealed many cysts ofpneumocystis carinii in the alveolar spaces. The authors consider that the promi-nence of the alvcolar eosinophilic granularexudate is suggestive of pneumocystispneumonia while the alveolar foamyexudate, characteristic for the histopatholo-gical diagnosis of pneumocystis pneumoniais not conspicuous enough. Further specialstainings, of course, are needed to establishthe diagnosis.更多还原