【摘要】 本文对合成的标题化合物进行了¹H NMR和¹³C NMR测试,证明该化合物具有酮式结构.通过饱和转移实验发现化合物中氮上的质子与DNISO-d_中的水有快速交换,经线型分析方法计算,求得交换体系的动力学参数:△H=8.4±0.5kcal·mol^-1;△S=-26.9±1.5cal·mol^-1·K^-1;△G=16.9kcal·mol^-1.更多还原

【Abstract】 The title compound has been prepared. Using ¹H NMR, ¹³C NMR and selected decoupling method, the compound is shown to exist in keto-form. Dynamic NMR method was used to investigate the exchange between NH in the title compound and water in DMSO-d₆. The rate process was calculated by complete line shape analysis method and activation parameters AH, △G, △S were found to be 8.4±0.5 kcal·mol^-1, 16.9±0.2 kcal·mol^-1 and -26.9±1.5 cal·mol^-1·K^-1 respectively.更多还原