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某医科大学250名教职工血清中抗-HBS水平调查

A survey of anti-HBs level in the sera of 250 workers in a medical college

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【作者】 赵世祯; 李艳军; 陈京; 买凯;

【Author】 Zhao shizheng, et al Hepatitis Division, Henan Institute of Medical Sciences

【机构】 河南省医科所肝炎研究室; 河南省医科所肝炎研究室;

【摘要】 本文应用单克隆抗体致敏的诊断血球作反向被动血凝检测HBsAg,用反向血凝中和抑制法检测抗体,以AUSAB EIA药盒作对照,两种方法符合率为80%,以RIA抗-HBc-Ⅱ药盒检测抗—HBc对某医大250名教职工血清进行了检测,结果HBsAg阳性率7.6%抗-HBs79.2%及抗-HBc78.4%。抽样抗体定量,最低为17.2mIU/mI,最高为638.1mlU/ml平均为296mlU/ml。提示:79.2%职工对HBV感染有免疫力。

【Abstract】 In this study, mono-clonal anti-HBs coated diagnostic RBC (Wuhan Institute of Biologics)was used to detect HBsAg by RPHA inhibition test With AUSAB EIA kits (Abbott)for comparison. The reletivity rate of the two methods was 80%.Anti-HBc was detected with RIA kits (Beijing Guang Hua Immuno-reagent Institutes). The sera. of 250 workers a medical college were tested. The results were as follows:The positive rates were 7.6%for HBsAg; 79.2% for anti-HBs; and 78.4% for anti-HBc Quantitative anti-HBs of spot check was detected. The minimunm level was 17.2 mIU/ml, maximum 638.1 mIU/ml, and mean 296 mIU/ml. The results suggest that 79.2% of the workers tested at the medical college had immunity against HBV infection.

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