【摘要】 本文应用特异性白细胞粘附抑制试验和灭活HBsAg疫苗皮试对245例慢性HBV感染者的细胞免疫状态和药物对其影响作了分析。采用灭活HBV全抗原卡介苗提取物治疗了158例,综合药物治疗87例。分别观察了两组治疗对慢性迁延型、慢性活动型和无症状HBsAg携带者细胞免疫的影响。提示用灭活HBV全抗原卡介苗治疗提高细胞免疫的作用比综合治疗组明显,对慢性迁延型和慢性活动型肝炎在治疗一年内细胞免疫有明显上升趋势。更多还原

【Abstract】 The effect of the drugs upon cellular immunity was studied by means of specific leucocyte adherence inhibition and skin test of inactivated HBsAg vaccine on 245 patients with chronic persistant or active hepatitis, and saymptomatic HBsAg carrier state. Of these, 158 were treated with inactivated HBV pan-antigen vaccine ptus BCG extract and 87 with other drugs. The results showed that the improvement of cellular immunity was more obvious in the patients treated with HBV pan-antigen vaccine plus BCG extract than in those treated with other drugs. The positive rates of cellular immunity tendency to increase gradually in the patients with chronic persistant with HBV pan antigen vaccine plus BCG extract for one year.更多还原