【摘要】 报告68例重症病毒性肝炎以一般支持疗法治疗30例,存活9例,加用支链氨基酸治疗28例,存活13例,而并用支链氨基酸及胰高糖素—胰岛素治疗10例,7例存活。支链氨基酸与胰高糖素—胰岛素并用可明显提高重症病毒性肝炎的存活率,并就其机制进行了讨论。更多还原

【Abstract】 Sixty-eight cases of severe viral hepatitis were divided into 3 groups. G-roup Ⅰ, 30 cases, treated with conventional (basic) therapy, of which 9 cases (9/30) are living, Group Ⅱ, 28 cases, treated with an additional remedy of branched-chain amino acid (BCAA), of which 13 cases (13/28) are surviving; Group Ⅲ, 10 cases, given with combined BCAA and glucagon-insulin therapy, of which 7 cases (7/10) are surviving. Pre and posttreatment liver function tests, blood sugar determinations, and amino acid spectrum analysis were performed in all 10 cases in Group Ⅲ. Rapid fading of jaundice, decrease of ALT, increase of BCAA/AAA ratio, and clinical alleviation are noticed. The survivor-patients recover gradually after the discontinuation of the BCAA and glucagon-insulin therapy. The authors consider that combination of BCAA and glucagon-insulin togather with general supportive treatment is superior to the conventional one in the management of severe viral hepatitis.更多还原