【摘要】 用昆明种雄性小鼠同时诱发了低碘和高碘甲状腺肿、根据低、高碘甲状腺肿发生到形成过程中组织象的改变与血清甲状腺激素的水平,初步研究认为,高碘地方甲状腺肿的发病机理是,在高碘影影下,甲状腺仍能合成和释放足量的甲状腺激素,甲状腺肿大是由于胶质在滤泡腔中淤积,使滤泡腔扩大所致。也就是说,低碘和高碘甲状腺肿的发病机理不同各有自己的发生机制。更多还原

【Abstract】 Two Kinds of goiter were formed in mice by feeding with iodine-deficient and iodine-excess foods. According to the changes of tissue image and the level of thyroid hormone in serum, during the forming process and occurrence of iodineexcess goiter,it is suggested that the thyroid gland was able to synthesis and release enough thyroid hormone in the condition of iodine-excess.Thyroid swelling was due to ssdiment of colloid in follicles, i.e.the mechanism of iodine-excess gojter formation is different from that of iodine-deficient goiter.更多还原