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大鼠颈内动脉恒速灌流测定脑血管阻力

Determination of Cerebral Vascular Resistance of Rats by Constant-rate Perfusion Apparatus per Arteria Carotis Interna

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【作者】 俞平; 黎七雄; 张志善;

【Author】 Yu Ping, et al (Department of Pharmacology, Hubei Mebical College)

【机构】 湖北医学院药理教研室; 湖北医学院药理教研室;

【摘要】 经颈内动脉恒速灌流测量大白鼠脑血管阻力,其结果如下:收缩压为90.4±4.99mmHg,脑血管阻力为84.1±5.9mmHg。注射去甲肾上腺素后可使这些值增加,而酚妥拉明可使这些值降低。

【Abstract】 The cerebral vascular resistences (CVR) of rats were measured by a constant-rate perfusion (1.82±0.17ml/min) apparatus. The results were as follows: system presure was 90.44±4.99mm Hg, and CVR was 84.1±5.9mm Hg. These values increased with intravascular injective of norepinephrine and decreased with phentolamine.

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