【摘要】 在54只兔的108例桡骨上分别造成1cm的骨缺损,将其平分为三组,分别植入脱钙同种异体骨、新鲜自体骨和新鲜同种异体骨。并于第1、3、5、7、10和13周,每组杀3只兔,用X线照片及组织学切片观察骨的愈合情况。结果发现新鲜异体骨植入后有排斥反应,而脱钙异体骨植入无此反应。实验证明脱钙同种异体骨是一种较好的植入物。彼优于新鲜异体骨,与新鲜自体骨植入无显著差异。新骨及软骨出现在植入物中而不在邻近宿主骨处,表明新骨形成可能是骨诱导作用的结果。更多还原

【Abstract】 Fifty four healthy rabbits with 108 limbs were divided into 3 grops with 36 limbs in each group, made 1 cm long radius defect in each limb. Group A was implanted by decalcified homogenous bone; roup B by fresh autogenous bone and group C by fresh homogenous bone. Then 3 rabbits with 6 limbs of each group were killed in the 1st, 3, 5, 7, 10 and 13th week respectively, to compare the bone healing roentgenologically and histologically There was receptive reaction in fresh homogenous bone implantation but not demonstrated in decalcified homogenous bone implantation. This experiment indicated that the bone healing of implantation with decalcified homogenous bone and fresh autogenous bone were faster than fresh homogenous bone and no receptive reaction. However there was no significant difference in the bone healing between the implantation with decalcified homogenous bone and fresh autogenous bone. The new cartilage and new bone appeared in the decalcified implant rather than near the host bone. This shows that the new bone is formed probablly by bone induction. Decalcified homogenous bone is a better implant.更多还原