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高温与CO联合作用下大鼠血脂及高密度脂蛋白-胆固醇水平的变化
CHANGES ON BLOOD LIPIDS AND HIGH DENSITY LIPOPROTEIN- CHOLESTEROL CONTENTS IN RATS UNDER THE COMBINED EFFECT OF HIGH TEMPERATURE AND CARBON MONOXIDE
【摘要】 Wistar大鼠被随机分为四组:A组(37℃+CO)、B组(37℃)、C组(25℃+CO)及D组(25℃)。 动物每天实验2小时,接触的CO浓度为600ppm。于实验的第7天及第21天测定各组动物血脂及HDL-C水平,发现第21天时A组和B组TG水平较第7天者明显升高,而各组(A、B、C和D组)的HDL-C水平均略低于第7天者。上述结果是诱发动脉粥样硬化的危险征兆。
【Abstract】 Wistar rats were randomly divided into four groups:group A(37 + CO), group B(37t) , group C(25+CO)and group D(25C). The rats were exposed to the different experimental condition with 600 ppm CO in the air in group A and C for two hours every day. The level of blood lipids and HDL-C was measured at the 7th and 21st day. It was found that the content of TG in group A and B at the 21st was markedly higher than those from group A and B at the 7th and that the content of HDL-C in all groups (A, B, C and D) at the 21st was slightly lower than that of all groups at the 7th. The result mentioned above is a risk factor for development of atherosclerosis.
- 【文献出处】 工业卫生与职业病 ,Industrial Health and Occupational Diseases , 编辑部邮箱 ,1986年04期
- 【被引频次】3
- 【下载频次】15